妈咪爱与培菲康辅助治疗新生儿黄疸的临床疗效比较

Clinical effect comparison of Mommy Love and Bifico in the adjuvant treatment of neonatal jaundice

目的:比较妈咪爱与培菲康辅助治疗新生儿黄疸的临床疗效。方法:将98例患儿随机分为治疗组和对照组,各49例。治疗组在常规治疗的基础上加用妈咪爱0.5 g/次,3次/d,思密达1.0 g+温开水15 mL,3次/d,口服;对照组在常规治疗基础上加用培菲康,半粒/次,3次/d,思密达1.0 g+温开水15 mL,3次/d,口服。观察治疗后2组患儿日平均胆红素下降值及胆红素下降至119.7μmol/L以下所需时间,并进行对比。结果:2组日平均胆红素下降值分别为(48.93±19.02)μmol/L和(36.61±17.33)μmol/L;胆红素下降至119.7μmol/L以下所需时间分别为(3.7±2.1)d、(5.5±2.2)d,2组比较差异有统计意义(P<0.05)。结论:妈咪爱联合思密达辅助治疗新生儿黄疸较培菲康联合思密达临床疗效好,能增加日均胆红素下降值,并能缩短治疗时间。

Objective： To compare the clinical effects of Mommy Love and Bifico in the adjuvant treatment of neonatal jaundice.Methods： 98 patients were randomly divided into the treatment group and the control group,49 patients each.The treatment group,based on the conventional therapy,was given Mommy Love,0.5 g / time,3 times /d,and Smecta,1.0 g ＋ warm water 15 mL,3 times/d,orally;the control group,based on the conventional therapy,was given Bifico,half a tablet / time,3 times /d,and Smecta 1.0 g ＋ warm water 15 mL,3 times/d,orally.The average daily decreasing value of bilirubin and the time of bilirubin decreasing to bellow 119.7 of patients in 2 groups were observed and compared.Results： The average daily decreasing values of bilirubin of both groups were（48.93±19.02） μmol /L and（36.61±17.33） μmol /L;the time of bilirubin decreasing to bellow 119.7μmol /L were respectively（3.7±2.1） d and（5.5±2.2） d.The differences of 2 groups were highly statistically significant（P〈0.05）.Conclusion： Mommy Love combined with Smecta had better clinical effect than Mommy Love combined with Bifico in the adjuvant treatment of neonatal jaundice and can increase the average daily decreasing value of bilirubin and shorten the treatment time.