我院2010年181例药品不良反应报告分析

Analysis of 181 cases of adverse drug reaction reports

目的掌握我院药品不良反应(ADR)特点、规律和临床表现,为临床合理用药提供依据。方法对我院2010年181例不良反应报表进行归纳分析。结果静脉滴注给药引起的不良反应发生率高,占65.75%;抗菌药物的不良反应报告例数最高,占46.97%,不良反应发生率最高的是头孢他定,占6.08%,最常见的临床表现为皮肤及其附件损害,占64.64%。结论应加强药品不良反应监测,临床应合理使用抗菌药物和静脉注射药物,减少或避免不良反应的发生。

Objective To study the regularity and characteristics of adverse drug reactions（ADR） occurred in our hospital.Methods The ADR reports of 181 cases collected from 2010 in our hospital were analyzed statistically.Results Of the total 181 ADR cases,119（65.75%）were induced by intravenous drip,anti-infective drug accounted for（45.31%）;The number of ADR cases induced by Ceftazidimed occupied the first place（6.08%）.Conclusion Importance should be attached to the reporting and monitoring of ADR,anti-infective drugs and intravenously injected drugs should be used rationally to reduce the incidence of ADR.