高同型半胱氨酸血症与颈血管斑块稳定性的关系探讨

The Study on the Association of Carotid Plaque with the Level of Hcy

目的:探讨高同型半胱氨酸血症(Hcy)与颈血管斑块稳定性的关系。方法:对86例在我院内科住院怀疑动脉硬化患者,采用彩色多普勒超声诊断仪10MHz高频探头检测患者双侧颈动脉,按超声检查结果分为3组:颈动脉无斑块组;稳定斑块组;不稳定斑块组。同时测定Hcy,记录血压并计算体质量指数,比较各组Hcy的差异。结果:各组年龄、性别、体质量指数、血压比较差异无统计学意义(P>0.05)。无斑块组Hcy水平明显低于不稳定斑块组、稳定斑块组(P<0.01),而不稳定斑块组Hcy水平又明显高于稳定斑块组(P<0.01)。结论:Hcy与颈动脉粥样斑块性质密切相关。

Objective： To explore the relationship between the character of the carotid plaque and homocysteine（Hcy）.Methods：The ultrasonography was performed with 10MHz in the ambi-carotid arteries in all the 86 patients of being suspected arteriosclerosis.According to the result,the patients were divided into 3 groups：no plaque group,stable plaque group and unstable plaque group.The level of Hcy was valued at the same time.Recorded blood pressure and the body msss index（BMI）.The relation between Hcy and carotid plaque was studied.Results：There were no significant differences among the groups in age,sex,BMI and blood pressure（P0.05）.The level of Hcy in nonplaque group was lower than that of other two groups（P0.01）.While there were also significant differences between the stable plaque group and no plaque group（P0.01）.Conclusion：The important relationship exists between the character of the Carotid plaque and Hcy.