具有抗肿瘤活性的齐墩果酸衍生物的研究进展

Advance in the Research on Oleanolic Derivatives with Anti-tumor Activity

齐墩果酸是一类广泛分布于植物体内的五环三萜类化合物,具有多种重要生物活性。本文综述了近年来发现的具有较好抗肿瘤活性的天然和合成的齐墩果酸衍生物的研究情况,并讨论了这些衍生物的作用机制。

Oleanolic acid exists widely in food, medicinal herbs and other plants and possesses many attractive biological activities. Recently, some natural and synthetic oleanolic derivatives were reported to have interesting anti-tumor activities. Herein, the authors reported the advance in the research on these oleanolic derivatives.