期刊文献+

同型半胱氨酸对人血管平滑肌细胞凋亡及凋亡相关蛋白表达的影响 被引量:4

下载PDF
导出
摘要 高同型半胱氨酸血症是动脉粥样硬化(AS)性血管疾病形成的独立危险因素,但其机制至今不完全清楚。起初,人们大都致力研究于同型半胱氨酸(Hcy)对内皮细胞的毒性作用,发现Hcy可损害内皮细胞,影响其舒张功能,近年来,
出处 《中国实验诊断学》 北大核心 2011年第11期1832-1834,共3页 Chinese Journal of Laboratory Diagnosis
  • 相关文献

参考文献6

  • 1Lee hY, Chae IH, Kim HS. Differential effects of homocysteine on porcine endothelial and vascular smooth muscle ceils[ J]. J Cardiovasc Pharmacol, 2002,39:643.
  • 2方丽娟,刘乃丰.细胞凋亡与动脉粥样硬化关系的研究进展[J].东南大学学报(医学版),2010,29(1):107-110. 被引量:23
  • 3Chen F, Eriksson P, Kimura T, et al. Apoptosis and angiogenesis are in- duced in the unstable coronary atherosclerotic plaque [J]. Coron Artery Dis,2005,16:191.
  • 4Buemi M, Marino D, Di Pasquale G, et al. Effects of homocysteine on pro- liferation, necrosis, and apoptosis of vascular smooth muscle cells in cul- ture and influence of folic acid[J]. Thromb Res. 2001;104:207.
  • 5Matsuhiko H, Takashi A. Caspase in renal development [ J]. Nephrol Dial Transplant, 2002,17(Sup9) : 8.
  • 6Kim SC, Rho MC, Lee HS, et al. Caspase-3-dependent apoptosis in vascu- lar smooth muscle cell by proteasome inhibition[ J]. J Cardiovasc Pharmacol, 2003,42(4) :554.

二级参考文献19

  • 1SCARABELLI T M,KNIGHT R,STEPHANOU A,et al.Clinical implications of apoptosis in ischemic myocardium[J].Curr Probl Cardiol,2006,31:181-264.
  • 2CHEN J,MEHTA J L,HAIDER N,et al.Role of caspases in ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells[J].Circ Res,2004,94:370-376.
  • 3KAVURMA M M,BHINDI R,LOWE H C,et al.Vessel wall apoptosis and atherosclerotic plaque instability[J].Thromb Haemost,2005,3:465-472.
  • 4ZEINI M,LPEZ-FONTAL R,TRAVéS P G.Differential sensitivity to apoptosis among the cells that contribute to the atherosclerotic disease[J].Biochem Biophys Res Commun,2007,363(2):444-450.
  • 5LEE H Y,YOU H J,WON J Y,et al.Forkheed factor,Foxo3a,induces apoptosis of endothelial cells through activation of matrix metalloproteinases[J].Arterioscler Thromb Vasc Biol,2008,28:302-308.
  • 6BANFI C,BRIOSCHI M,WAIT R.Proteome of endothelial cell-derived procoagulant microparticles[J].Proteomics,2005,17:4443-4455.
  • 7SUKHANOV S,HIGASI Y,SHAI S Y,et al.Novel effect of oxidized low-density lipoprotein:cellular ATP depletion via downregulation of glyceraldehyde-3-phosphate dehydrogenase[J].Circ Res,2006,99(2):191-200.
  • 8LESKINEN M J,HEIKKIL H M,SPEER M Y,et al.Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-kappaB-mediated survival signaling[J].Exp Cell Res,2006,312(8):1289-1298.
  • 9TABAS I.Signal transduction pathways in free cholesterol-loaded macrophages:cell biological insight into the progression of atherosclerosis[J].International Congress Series,2004,1262:392-395.
  • 10HUNG Y C,HONG M Y,HUANG G S.Cholesterol loading augments oxidative stress in macrophages[J].FEBS Letters,2006,580(3):849-861.

共引文献22

同被引文献41

  • 1郭峰,朱炳阳,迟秀玲,黄红林.迷迭香酸抗过氧化氢诱导血管平滑肌细胞凋亡作用的研究[J].中国药理学通报,2007,23(3):365-370. 被引量:26
  • 2Roger VL,Go AS,Lolyd-jones DM,et al.Heart disease and stroke stastistics-2011update,a report form American Heart Association[J].Circulation,2011,123(4):e12-e209.
  • 3Xia Y P,Wang L H,Fan Y R.Cell apoptosis and endoplasmic reticulum stress[J].Pharm Clin Res,2010,18(3):291-298.
  • 4Kim J,Parrish AB,Kurokawa M,et al.Rsk-mediated phosphorylation and 14-3-3εbinding of Apaf-1 suppresses cytochrome c-inducedapoptosis[J].EMBO J,2012,31(5):1279-1292.
  • 5Lindsay J,Esposti MD,Gilmore AP.Bcl-2 proteins and mitochondria-Specificity in membrane targeting for death[J].Biochim Biophys Acta,2011,1813(4):SI:532-539.
  • 6Hetz C.The unfolded protein response;controlling cell fate decision under ER stress and beyond[J].Nat Rev Mol Cell Biol,2012,13(2):89-102.
  • 7Gorman AM,Healy SJ,J ger R,et al.Stressmanagement at the ER;regulators of ER stress-induced a poptosis[J].,Pharmacol ther,2012,134(3):306-316.
  • 8Rao RV,Hermel E,Castro-Obregon S,et al.Coupling endoplasmic reticulum stress to the cell death program.Mechanism of Caspase activation[J].J Biol Chem,2001,276(36):33869-33874.
  • 9Chen XP,Xun KL,W u Q,et al.Oxidized low density lipopro te in receptor-1 mediates ox idized low density lipoproteininduced apopto sis in human umbilica lvein endothe lial cells:role of reactiv eoxygen species[J].Vasc Pharma col,2007,47(1):1-9.
  • 10Ross R.Atheroscl erosi s:An infl am mat ion disease[J].NEngl J Med,1999,340(2):115-126.

引证文献4

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部