摘要
目的探讨吉林地区婴幼儿病毒性腹泻的病原学特点,为病毒性腹泻的防控提供参考依据。方法采集2007年10月-2008年11月在吉林市儿童医院就诊的5岁以下腹泻儿童粪便标本,并进行病原学检测分析,同时对患儿家长进行面对面问卷调查。结果 417份粪便标本实验室检测结果显示,轮状病毒的阳性检出率最高,为51.80%,然后依次为杯状病毒(18.00%)、星状病毒(6.70%)、肠道腺病毒(3.40%)。对上述四种病毒与感染者性别、年龄、生活环境以及发病季节的比较发现,除轮状病毒与性别、年龄、发病季节和杯状病毒与发病季节有统计学意义外(P<0.05),其余均无统计学意义。轮状病毒G血清型检测中,以G3型为主,占35.73%;P基因型检测中,以P8型为主,占35.01%。结论轮状病毒是吉林地区婴幼儿病毒性腹泻的主要病原体,主要血清型为G3型,主要基因型为P8型;杯状病毒、星状病毒和肠道腺病毒也是重要的病原体。
Objective To study the aetiology characteristics of virus diarrhea among infants by surveillance in Jilin city,and provide the credible evidence with prevention and treatment of the disease.Methods Detected the virus from the diachorema specimens of diarrhea infants under 5 years of age in Jilin Children＇s Hospital from 2007 to 2008,and inquired the infants＇ parents face to face.Results Among 417 specimens,the positive rate of RV is the highest（51.80%）,then followed by HuCV（18.00%）,AstV（6.70%）,AdeV（3.40%）.Comparison of these four types virus incidence with infected sex,age,living environment and seasonal,RV have statistically significant with the gender,age,season of infants（P〈0.05）,others all have no statistically significant.Specimens of RV-G tested by serotyping,G3 was the predominan type（35.73%）,in the test of genotype P,P8 wag the predominan type（35.01%）.Conclusion RV is the dominance etiological agent of infantile diarrhea in Jilin city.The predominan serotype is G3,the predominan genotype is P8.HuCV,AstV and AdeV ale were also the important etiological agents.
出处
《中国实验诊断学》
北大核心
2011年第11期1878-1881,共4页
Chinese Journal of Laboratory Diagnosis
