产程发动前后环氧化酶-2(COX-2)核因子KappaB P65(NF-KBP65)在平滑绒毛膜上的表达
摘要
众所周知,分娩发动的必备条件是胎儿的成熟和母体的准备。母体准备包括,子宫由分娩前期(0期)稳态,进入敏感期即分娩准备期(1期),此期子宫生物学上的主要变化为缩宫素受体大量增加、子宫下段及宫颈成熟、蜕膜与胎膜自分泌旁分泌效应的启动。有关分娩动因已有许多学说,但仍不清楚触发分娩启动的始动因素,无论神经内分泌因素抑或胎盘及胎儿神经内分泌因素均缺乏母胎之间启动信号的确认。
出处
《中国实验诊断学》
北大核心
2011年第11期1939-1940,共2页
Chinese Journal of Laboratory Diagnosis
参考文献6
-
1Ghosh S, May M J, Kopp EB. NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses[J]. Annu Rev lmmunol, 1998, 16: 225.
-
2Martha L, Michael P, Harry MG, et al. Nuclear Factor Kappa B Regulation of Proinflammatory Cytokines in Human Gestational Tissues In Vitro Biology of Reproduction [ J ]. 2002,67 : 668.
-
3Allport VC, Pieber D, Slater DM, et al. Human labour is associated with nuclear factor-kappaB activity which mediates cyelooxygenase-2 expression and is involved with the 'functional progesterone withdrawal' [J]. Molecular Human Reproduction,2001,7:581.
-
4Terzidou V, Lee YS, Thornton S, et al. Identification of the response region on the oxytocin receptor (OTR) promoter which is important for the syner- gistic transactivation of OTR by C/EBPbeta and NF-kappaB transcription factors[ J]. Journal of the Society for Gynecologic Investigation, 2003,10: 190A.
-
5Olson DM. The role of prostaglandins in the initiation of parturition [ J ]. Best Practice and Research: Clinical Obstetrics and Gynaecalogy, 2003, 17: 717.
-
6Stjernholm VY, Stygar D, Mansson C, et al. Factors involved in the inflammatory events of cervical ripening in humans[J]. Rep rod Biol Endocrino, 2004,12 (1) :74.
-
1赵红,闫秀娟.足月分娩前后羊水中白细胞介素1和白细胞介素8含量变化及其相关性分析[J].中国中医药现代远程教育,2009,7(12):203-203.
-
2陈桢玥,陆国平,龚兰生.核因子κappaB与动脉粥样硬化[J].上海医学,2002,25(9):602-604. 被引量:1
-
3陆光华,张美祥,张依群,李培,王定胜,卢源,张小蕾.吲达帕胺对高血压病左室肥厚及神经内分泌因素的影响[J].贵阳医学院学报,1993,18(1):53-56.
-
4陈炜,王焱,吴汉宁,陆非平,李华贵,杜平,张静姝.硝苯地平缓释片对高血压患者血管活性肽的影响及意义[J].中华心血管病杂志,2005,33(1):89-89. 被引量:10
-
5金镇,王伟,马妍,关哲,吴彬.分娩状态下子宫下段组织中基质金属蛋白酶9表达的变化及地西泮对其的影响[J].中华妇产科杂志,2005,40(4):260-263. 被引量:13
-
6邢惠莉,胡静芳.孕妇得了糖尿病怎么办[J].家庭用药,2002(8):9-9.
-
7杨丽霞,郑甲林,齐峰,王先梅,郭传明,苗贵华,任丽,李明秋.急性冠状动脉综合征患者核因子κB和基质金属蛋白酶9的变化及临床意义[J].中国循环杂志,2010,25(5):352-355. 被引量:6
-
8潘晨,张震,刘晓平.肠缺血再灌注损伤与NF-кB研究进展[J].安徽医药,2012,16(11):1564-1565. 被引量:2
-
9阎爱国,荣芳,田苇.高血压患者左心室肥厚与胰岛素抵抗的相关性研究[J].山东医药,2005,45(4):14-14.
-
10杨丽霞,郑甲林,齐峰,王先梅.冠心病患者核因子κB的变化及其临床意义[J].中国循证心血管医学杂志,2012,4(3):204-207. 被引量:6