布地奈德混悬液联合肾上腺素雾化吸入治疗毛细支气管炎的疗效分析

The efficacy about budesonide combined use of epinephrine inhalation aerosol inhalation treatment of bronchiolitiS

目的探讨布地奈德混悬液联合肾上腺素雾化吸入治疗毛细支气管炎的疗效及安全性。方法将128例毛细支气管炎患儿随机分为两组，均采用综合治疗，治疗组在常规抗感染、对瘫治疗的基础上予布地奈德混悬液与肾上腺素雾化吸入，疗程5～7d，对照组在常规抗感染、对症治疗的基础上，单用布地奈德混悬液雾化吸入，疗程7d。观察两组患儿症状、体征消失的时间、住院时间，并进行临床疗效分析。结果治疗组咳嗽、喘、憋症状缓解，呼吸困难好转，哮呜音、湿哕音消失时间，住院时间明显缩短，与对照组比较差异有统计学意义（P≤0．05）。结论布地奈德混悬液联合肾上腺素雾化吸入治疗毛细支气管炎，对急性期症状缓解优势明显，可缩短病程，减少住院时间，疗效肯定．使用安全。

Objective To investigate the efficacy and secure of budesonide combined with nebulized epinephrine inhalation in the treatment of capillary bronchiolitis. Methods One hundred and twenty - eight children with capillary bronchil- itis were randomly divided into tow groups. Both groups were given synthetical treatment. Treatment group received traditional therapy such as anti - influence and actcome, treatment additional budesonide and epinephrine inhalation aerosol inhalation, the period of treatment was 5 ~ 7 days. The control group received above and were treatment 7 days with budesonide only. The disappearance of the clinical symptoms and signs, during hospital stay were observed and clinical therapeutic effects in 2 groups were evaluated. Results The clinical with the symptoms including cough wheezing rale, difficulty breathing, pulmonary rales disappeared dry time and the hospital stay were significantly shortened. The prevalence rate in control group decreased significantly（ P 〈 O. 05 ）. Conclusion To reduce the acute symptoms of children with budesonide combined use of epineph- rine inhalation aerosol inhalation treatment of bronchiolitis the more obvious advantages. It could shorten the course of disease and hospital stay, achieve excellent efficacy, use safe.