雷公藤多苷片生殖系统毒性及增效减毒研究进展

Impaired Genital System of Tripterygium Wilfordii Polglycosidium and Research Advance of Compatibility for Attenuation Synergia

(1)检索雷公藤多苷片致生殖系统毒性的相关文献,探讨雷公藤多苷片使用累积剂量和时间与生殖系统损伤之间的相关性,为临床安全应用雷公藤多苷片提供指导。(2)检索雷公藤多苷片的增效减毒的相关文献,分析雷公藤多苷片与其他药物相互作用机理,最终为临床高效应用雷公藤多苷片提供循证依据。

（1）Related data of Impaired Genital System of Tripterygium Wilfordii Polglycosidium（TWP）were retrieved,and to explore the Correlation of TWP cumulative dosage and time to Impaired Genital System,which can be safe for clinical application of TWP to provide guidance.（2）To retrieval efficiency TWP attenuated the relevant literature,and to make analysis of the Interaction mechanism of TWP with other drugs,which can provide evidence of efficient application of TWP in the final clinical.