有氧运动对老年高脂血症患者血脂及超敏C反应蛋白水平的影响

Effects of Aerobic Exercise on the Blood Lipid and High-sensitivity C-Reactive Protein in Elder Patients with Hyperlipidemia

目的:观察有氧运动对老年高脂血症患者血脂及超敏C反应蛋白(hs-CRP)水平的影响。方法:60例老年高脂血症患者随机分为对照组(30例)和运动组(30例),运动组患者进行有氧运动24周,分别于运动前后检测患者血脂和血清hs-CRP水平。结果:24周后,运动组患者血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)和hs-CRP水平均显著低于运动前和对照组(P<0.01或P<0.05),高密度脂蛋白胆固醇(HDL-C)显著高于运动前和对照组(P<0.05);对照组患者血脂及血清hs-CRP水平无明显变化(P>0.05)。结论:有氧运动不但对老年高脂血症患者血脂有调节作用,还可降低血清hs-CRP水平,减轻炎症反应。

Objective：To observe the effects of aerobic exercise on the levels of blood lipid and high-sensitivity C-reactive protein（hs-CRP）in elder patients with hyperlipidemia.Methods：Sixty elder patients with hyperlipidemia were randomly divided into control group（n=30）and exercise group（n=30）,the patients of exercise group were Aerobic exercise for 24 weeks.Serum levels of total cholesterol（TC）,TG,HDL-C,LDL-C and hs-CRP at the beginning and after 24 weeks of exercise were measured.Results：After 24 weeks of exercise,compared with pre-exercise and control group,the serum TC,TG,LDL-C and hs-CRP were decreased,however the serum HDL-C was increased in exercise group patients.Pre-and post-exercise,no significant difference on blood lipid and high-sensitivity C-reactive protein levels was found in the control group.Conclusion：Aerobic exercise may not only mediate blood lipid level but also decrease serum hs-CRP and inflammation reaction in elder patients with hyperlipidemia.