慢性胰腺炎的危险因素分析

Risk factors of chronic pancreatitis

慢性胰腺炎病因复杂。近年来针对慢性胰腺炎的流行病学研究发现,慢性胰腺炎发病率逐年升高且病因构成发生改变。酒精虽然仍是导致慢性胰腺炎最常见的危险因素,但其比例显著下降,酒精摄入量与慢性胰腺炎的患病风险密切相关。长期吸烟也被认为是慢性胰腺炎相关的独立危险因素。其他病因如遗传性、自身免疫性及特发性慢性胰腺炎等发病率较前增加。在我国,酒精已超越胆道疾病成为慢性胰腺炎的主要病因。

Risk factors of chronic pancreatitis （CP） are complex. Many epidemiology studies have been reported that there were an in creased incident rate and alternation of etiology of CP in recent years. The prevalence of alcohol consumption, which is still the most important risk factor for CP, has been declined. When stratified by drinking status, very heavy alcohol consumption has been demonstrated to be significantly associated with CP. In addition, cigarette smoking is also a dosedependent, independent risk factor of CP. Other types of CP, such as hereditary, autoimmune and idiopathic CP, also increased recently. In our country, alcohol intake, but not biliary tract disease or gallstone, has become the most common cause of CP.