全方向M型超声心动图评价2型糖尿病患者左室收缩同步性的研究

Evaluation of Left Ventricular Systolic Synchronization of Patients with Type 2 Diabetes Mellitus by Omni-Directional M-Mode Echocardiography

目的应用全方向M型超声心动图评价2型糖尿病患者左室心肌局部收缩运动同步性。方法选择2型糖尿病患者40例(糖尿病组)、健康者30例(对照组),应用二维超声心动图测量左心房内径(LA)、左心室内径(LV)、室间隔厚度(IVS)、短轴缩短率(FS)、左心室舒张末期容积(EDV)、等容收缩时间(IVCT)、左室射血分数(LVEF),应用全方向M型超声心动图测量收缩期运动速度达峰时间(Ts)和12节段的Ts的标准差(Ts-sd)及最大时间差(Ts-dif)。结果糖尿病组LA、IVS、EDV均大于对照组(P<0.05),而FS小于对照组(P<0.05);左心室短轴二尖瓣及乳头肌水平糖尿病组各室壁的Ts和Ts-sd大于对照组(P<0.05);两组Ts-dif差别无统计学意义(P>0.05)。结论糖尿病患者早期就可出现左室局部心肌收缩运动不同步。全方向M型超声心动图可准确定量评价其收缩运动的同步性。

Objective To assess left ventricular systolic synchronization of the patients with type 2 diabetes mellitus（DM） by omni-directional M-mode echocardiography（OME）.Methods There were 40 patients with DM（DM group） and 30 normal subjects（control group） in the study.Two-dimentional echocardiography was used to measure left atrial diameter（LA）、left ventricular diameter（LV）,ventricular septal thickness（IVS）,fractional shortening（FS）,left ventricular end-diastolic volume（EDV）,isovolumic contraction time（IVCT）,left ventricular ejection fraction（LVEF）.Time to peak myocardial systolic velocities（Ts）,standard deviation（Ts-sd） and maximum difference（Ts-dif） of Ts were obtained from OME.Results Compared with the control group,LA,IVS,EDV were increased and FS was reduced in DM group（P0.05）;Ts of each segment of left ventricular short axis at the mitral valve level and the papillary muscle level were longer,and Ts-sd was increased in DM group（P0.05）;There was not significantly difference on Ts-dif between two groups（P0.05）.Conclusion Left ventricular myocardial contraction can show asynchronous early in patients with DM,OME can be used to evaluate quantificationally left ventricular systolic synchronization.