两种窝沟封闭术疗效比较的系统评价

Enameloplasty sealant technique versus conventional sealant technique for caries prevention:A systematic review

目的:系统评价釉质成形封闭术(enameloplasty sealant technique,EST)和普通窝沟封闭术(conventional sealant techni-que,CST)的临床疗效。方法:采用Cochrane系统评价的方法,计算机检索我国有关EST与CST的临床随机对照研究的文献,检索时间截止2010年。在严格筛选资料和质量评价的基础上,采用RevMan 5.0软件对纳入的研究进行Meta分析。结果:共检索到38篇相关文献,最终有9篇文献符合纳入标准。Meta分析结果显示,EST组术后1年新龋发生率与CST组差异无统计学意义[OR=0.45,95%CI(0.10,2.05)],其它时期防龋效果及3年封闭剂保存率均优于CST组,差异有统计学意义[OR=2.67,95%CI(1.91,3.73)]。结论:现有证据表明,窝沟釉质成形封闭术的防龋效果优于普通窝沟封闭术。

Objective： To access effectiveness of enameloplasty sealant technique（EST） versus conventional sealant technique（CST） for preventing caries.Methods： The Cochrane reviewers＇ handbook was followed.Domestic published articles before 2011 were selected by computer.All the retrieved studies were clinical control trials related to EST versus CST for preventing caries.The quality of the included studies was critically evaluated and data were analyzed by the RevMan 5.0 software.Results： 38 articles were found,only 9 were included.Meta-analysis showed that there were no significant differences in the caries prevalence rate between EST and CST groups in the first year（OR=0.45,95%CI 0.10 to 2.05）,a significant lower caries prevalence rate was found in the second and third years in EST groups.The rate of sealant reservation in EST group was significantly higher than that in CST group in the first,second and third years.Conclusion： Based on the current evidence,EST is superior to CST in preventing pit and fissure caries.