摘要
细胞间黏附分子的表达变化与肿瘤的发展、浸润、转移有着密切的关系。同时,肿瘤的发展也是多种分子在不同阶段共同参与调控的结果。阐明它们表达水平的变化与恶性肿瘤发生发展不同阶段的相互关系及其规律,对恶性肿瘤的诊断、治疗以及预后判断有重要意义。本文就上皮组织钙黏素(E-cadherin)以及其他多种相关分子在口腔鳞状上皮恶性肿瘤中的表达情况做一综述。
Intercellular adhesion molecules play important role in tumor development,invasion and metastasis.The development of cancer is regulated by a variety of molecules at different stages.Thus,clarifying the relationship and regular pattern of these molecules and the development of malignances in different stages is beneficial for the diagnosis,treatment and prognosis of the tumors.In this article,the expression of epithelial cadherin(E-cad) and many other related molecules in oral squamous cell cancer are reviewed.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
2011年第6期851-855,共5页
Journal of Practical Stomatology
关键词
口腔鳞癌
E-钙粘素
分子调控
Oral squamous cancer
E-cadherin
Molecular regulation