重症监护病房患者非发酵菌的分布及药敏性分析

Distribution and drug-sensitivity analysis of nonfermenters in patients of ICU

目的:分析医院重症监护病房患者非发酵菌感染及其耐药情况。方法:回顾性分析2010年医院重症监护病房患者分离的非发酵菌,对其检出情况及药敏结果进行统计分析。结果:共检出1047株非发酵菌,检出率为44%,居前3位的依次是铜绿假单胞菌(51.13%)、鲍氏不动杆菌(21.45%)、嗜麦芽寡养单胞菌(10.38%);3种常见的非发酵菌对常用的抗菌药物耐药性均较高。结论:医院重症监护病房非发酵菌检出率高,耐药性强。

Objective：To explore the infection status and antibiotics resistance of non-fermenting bacteria in patients of intensive care unit,so as to guide rational application of antibiotics in clinic.Methods： The non-fermenting bacteria isolated from sputum of patients in intensive care unit in 2010 were identified and their drug sensitivity results were analyzed.Results： A total of 1047 strains of non-fermenting bacteria were isolated,performing the detection rate of 44%.The top three were Pseudomonas aeruginosa（50.13%）,Acinetobacter baumannii（21.45%）,Stenotrophomonas maltophilia（10.38%）.They were high resistance to common antimicrobial agents.Conclusion： Non-fermenting bacteria isolated from hospitalized patients in intensive care unit show higher isolation rate and multidrug resistance.Therefore,pathogenic bacteria identification and antimicrobial susceptibility test should be strengthened to instruct antibiotics properly in clinic.