育龄妇女沙眼衣原体感染与不良孕产结局的关系

Relationship between chlamydia trachomatis infection and adverse pregnant outcome among women at child-bearing age

目的:探讨育龄妇女沙眼衣原体感染与不良孕产结局的关系。方法:采用荧光定量聚合酶链反应(FQ-PCR)技术对1969例育龄妇女宫颈分泌物标本进行沙眼衣原体(CT)检测。结果:总阳性率10.51%。继发不孕者阳性率为16.78%,显著高于普通孕妇的9.45%(P<0.01)。CT阳性孕妇异常妊娠结局率为27.63%,显著高于阴性孕妇的10.15%(P<0.01)。结论:育龄妇女CT感染是造成继发不孕、不良妊娠结局包括流产、早产等的重要因素之一。

Objective：To explore the relationship between chlamydia trachomatis（CT） infection and adverse pregnant outcome among women at child-bearing age.Methods：FQ-PCR was used to detect CT in cervical secretion samples of 1 969 women at child-bearing age.Results：The total positive rate was 10.51%.The positive rate of women with secondary infertility was 16.78%,which was significantly higher than that of normal pregnant women（9.45%）（P0.01）.The rate of adverse pregnant outcome was 27.63% in CT-positive pregnant women,which was significantly than that in CT-negative pregnant women（10.15%）（P0.01）.Conclusion：CT infection among women at child-bearing age might be one of the important factors inducing secondary infertility and adverse pregnant outcomes including abortion,premature birth,and so on.