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高龄冠心病患者双联抗血小板长期治疗的安全性 被引量:23

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摘要 虽然介入治疗在冠心病治疗中占重要位置,但在多方面因素作用下,我国仍有绝大部分高龄冠心病患者采用保守治疗控制病情。血小板活化、聚集、血栓形成是冠状动脉闭塞的中心病理环节〔1〕,因此抗血小板聚集治疗是冠心病的主要用药之一,但高龄患者往往是出血高危人群〔2〕,长期双联抗血小板治疗时两种药物剂量如何选择,安全性如何?国内外循证医学方面证据不多。本研究拟回顾性分析高龄冠心病患者单用阿司匹林及阿司匹林+小剂量氯吡格雷双联抗血小板的安全比较,为高龄冠心病患者安全有效的抗血小板聚集治疗提供依据。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第22期4448-4449,共2页 Chinese Journal of Gerontology
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