摘要
转移相关基因(MTA)是一个与肿瘤发生和进展密切相关的基因家族。最近的研究表明,MTA家族成员在多种人类肿瘤组织中表达异常升高,并通过多种机制参与肿瘤的侵袭、转移及血管生成。MTA可能是多种恶性肿瘤发生与进展相关的主要调节分子家族之一。
MTA is a gene family closely related with carcinogenesis and cancer progression. According to many recent studies, the member of MTA overexpressed in a wide range of human cancers and was involved in invasion, metastasis and angiogenesis. MTA may be one of main regulatory molecules family in the procession of carcinogenesis and progression.
出处
《基础医学与临床》
CSCD
北大核心
2011年第12期1406-1409,共4页
Basic and Clinical Medicine
关键词
转移相关基因
肿瘤
metastasis-associated gene
cancer