牙周健康状况与慢性阻塞性肺病的流行病学调查报告

Epidemiological investigation of the relationship between periodontal health status and COPD

目的通过大量调查以探讨牙周健康状况与慢性阻塞性肺病(COPD)的流行病学关系。方法从2009年9月10日至2010年3月14日,杭州市部分干部及知识分子共计1 945名接受了口腔健康检查(CPI指数和附着丧失量AL)和全身状况评价(年龄、吸烟程度、体重指数和全身系统疾病情况)。结果 1 945名受检者中共有253名患者被确诊为COPD,患病率13.02%。COPD组各区段AL均值普遍高于非COPD组。结论①杭州市高层次高收入人群COPD患病率为13.02%,与全国水平基本一致。②杭州市高层次高收入人群的牙周情况与全国水平相比相对较差,其人群的牙周保健意识仍待提高。③COPD与牙周病存在联系,最高牙周附着丧失量是可能造成COPD发病的危险因素之一(OR=1.512)。④造成AL与COPD相关性的可能因素为a.两者具有共同的危险因素(吸烟、营养不良、基础性疾病等);b.两者具有共同的免疫反应机制。

Objective To explore epidemiological relationship between periodontal health status and COPD by a number of investigation.Methods 1945 volunteers who were cadres or intellectuals in Hangzhou were recruited in the study.They received oral health examination including community periodontal index（CPI） and periodontal attachment loss（AL）,and systemic evaluation including age,smoking,BMI and systemic conditions.Results 253 of 1 945 volunteers were diagnosed with COPD,and prevalence rate was 13.02%.The results showed that the subjects with COPD had significantly more mean AL than those without COPD.Conclusions 1.The prevalence of COPD in group with better socioeconomic status and good education in Hangzhou is consistent with the national level.2.The periodontal health status in groups with better socioeconomic status and good education in Hangzhou is poorer than the national average condition.They should improve their awareness of periodontal health care.3.The maximum AL is one of the risk factors that may cause COPD（OR=1.512）,so periodontal disease has the relation with COPD.4.The possible factors that cause the association between periodontal attachment loss and COPD： a.the same risk factors such as smoking,malnutrition,basic disease,etc.b.the same immune response mechanism.