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IGFl-R/PI3K/Akt信号通路在妊娠期心脏重构中的作用

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摘要 心脏曩构(cardiacremodeling)是心脏为适应一系列病理生理变化Ⅲ发生分子和暴l大1表达变化,导敛心脏的大小、形状和功能发生改变,一般认为,妊娠期心脏重构属于生理性变化,但是舟妊娠期心脏仍会发生一些病理观象,如妊娠晚期f{{现左心窜舒张功能下降、甚至出现阳产期心肌病而危及孕妇的。
作者 刘华 林建华
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2011年第11期861-863,共3页 Chinese Journal of Obstetrics and Gynecology
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  • 1Ro A, Frishman WH. Peripartum cardiomyopathy. Cardiol Rev, 2006, 14:35-42.
  • 2Catalucci D, Latronico MV, Ellingsen O, et al. Physiological myocardial hypertrophy : how and why? Front Biosci, 2008, 13 : 312-324.
  • 3Bridges E J, Womble S, Wallace M, et al. Hemodynamic monitoring in high-risk obstetrics patients, I. Expected hemodynamic changes in pregnancy. Crit Care Nurse, 2003, 23 : 53-62.
  • 4Virgen-Ortiz A, Matin JL, Elizalde A, et al. Passive mechanical properties of cardiac tissues in heart hypertrophy during pregnancy. J Physiol Sci, 2009, 59:391-396.
  • 5Hayakawa Y, Chandra M, Miao W, et al. Inhibition of cardiac myocyte apoptosis improved cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha (q) transgenic mice. Circulation, 2003, 108:3036-3041.
  • 6McMullen JR, Jennings GL. Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure. Clin Exp Phannacol Physiol, 2007, 34 : 255-262.
  • 7Miyamoto S, Rubio M, Sussman MA. Nuclear and mitochondrial signalling Akts in cardiomyocytes. Cardiovasc Res, 2009, 82 : 272-285.
  • 8Frystyk J, Ledet T, Moiler N, et al. Cardiovascular disease and insulin-like growth factor L . Circulation, 2002, 106:893-895.
  • 9Li B, Setoguchi M, Wang X, et al. Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart. Circ Res, 1999, 84:1007-1019.
  • 10Yamashita K, Kajstura J, Diseher DJ, et al. Reperfusion- activated Akt kinase prevents apoptosis in transgenic mouse hearts overexpressing insulin-like growth factor-1. Circ Res, 2001, 88: 609-614.

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