腰椎间盘退变性疾病危险因素分析及治疗

Study on risk factors for lumbar degenerative disc disease

目的探索腰椎间盘退变性疾病的危险因素,为该类疾病的预防和治疗提供依据。方法采用病例对照研究方法,在2008-06-2010-03我院脊柱专科门诊确诊为腰椎间盘退变性疾病的960例患者中随机抽取118例设为病例组,体检中心随机抽取167例无下腰痛病史人员为对照组,问卷调查性别、年龄、身高、体重、职业工种、腰背部外伤史、腰椎疾病家族史等,建立单因素四格表资料的F检验和多因素非条件Logistic回归分析。结果单因素四格表资料的F检验和非条件Logistic回归分析结果显示超重、固定工作体位、腰背部外伤史、腰椎疾患家族史是该地区居民腰椎间盘退变的危险因素。结论腰椎间盘退变性疾病患者的发病与肥胖、职业工种、腰椎疾患家族史、腰背部外伤史等因素有密切的关系,治疗应个体化多样化,并加强健康卫生宣教。

Objective To explore risk factors for lumbar degenerative disc disease.Methods With a case-control study,118 cases of 960 patients diagnosed by CT/MRI as lumbar degenerative disc disease and 202 controls without low back pain,questionnaires were used to collect information on the exposure to risk factors including gender、age、occupation、weight、back injury history、family history of lumbar degenerative disc disease and analyzed by non-conditional logistic method.Results Through non-conditional logistic regression analysis,Obesity、family history of lumbar degenerative disc disease、back injury history、permanent work pose were the risk factors among residents from the area.Conclusion Obesity、Family history、back injury history、permanent work pose are the main risk factors for lumbar degenerative disc disease.