超声造影不同增强模式对良恶性甲状腺结节的鉴别价值

Diagnostic value of different enhancement modes of contrast-enhanced ultrasound in the differention of benign and malignant thyroid nodules

目的:探讨甲状腺良恶性结节实时灰阶超声造影的增强表现及其鉴别诊断价值。方法:46例甲状腺病变患者先行常规二维超声及彩色多普勒检查后,再行超声造影检查,观察甲状腺结节的增强模式,将其分为不均匀强化、均匀强化、环形强化及不强化;同时观察甲状腺结节造影前后测值的变化。结果:46例患者共49个甲状腺结节(23个恶性结节、26个良性结节),超声造影表现为不均匀强化者中良性3例、恶性16例,呈均匀强化的良恶性结节均为6例,呈环形强化者中良性16例、恶性1例,一个良性结节呈不强化,良恶性结节在不均匀强化和环形强化方面差异有显著性意义;甲状腺良恶性结节在均匀强化方面差异无显著性意义。结论:超声造影增强模式对于甲状腺结节良恶性的鉴别具有重要临床诊断价值。

Objective：To investigate the diagnostic value of different enhancement modes of real-time gray contrast-enhanced ultrasound for difference between benign and malignant thyroid nodules.Methods：After taking the routine two-dimensional ultrasound and color Doppler examination,46 patients with thyroid lesion symptoms underwent contrast-enhanced ultrasound imaging.According to the modes of enhancement the thyroid nodules would be divided into following four typies：inhomogeneous,homogeneous,ring enhancement and non-enhancement;Meanwhile the changes in measured value of thyroid nodules before and after contrast enhanced ultrasound imaging were observed.Results：Fourty-nine thyroid nodules（23 malignant nodules,26 benign nodules） were found in 46 cases,including the inhomogeneous enhancement of benign in 3 cases and malignant in 16 cases,homogeneous enhancement of benign and malignant nodules in 6 cases each,ring enhancement of benign in 16 cases and malignant in 1 case,non-enhancement in 1 benign nodule.There was statistically significant difference between benign and malignant nodules in terms of inhomogeneous enhancement and ring enhancement.Conclusion：It has shown that the enhanced mode of contrast-enhanced ultrasound has important value in the identification of benign and malignant thyroid nodules.