摘要
目的:探讨口腔黏膜扁平苔藓(OLP)癌变的诊断和以手术为主的综合治疗的效果。方法:对1998—2007年间收治的经临床初诊并经病理学证实的64例OLP癌变患者,从临床角度进行回顾性分析。为便于观察,均选择位于颊黏膜的患者,在PVP诱导化疗21d后选择根治性手术。结果:术后1、3年的生存率分别为87.50%和75.00%,局部复发11例(17.18%)。结论:探讨OLP癌变的诊断标准,解决了Krutchkoff等提出的不同意OLP癌变的3点质疑;OLP癌变治疗的重点在于综合治疗。
PURPOSE： To discuss the diagnosis and comprehensive treatment based on operation and close observation of canceration of oral lichen planus（OLP）.METHODS： Sixty-four patients with cancerous OLP were retrospectively analyzed,who were clinically diagnosed and pathologically confirmed to be OLP canceration from 1998 to 2007.Only patients who had buccal mucosal lesions were selected.After 21 days of PVP induction chemotherapy,all the patients underwent radical resection.RESULTS： The 1-and 3-year survival rate was 87.50% and 75.00%,respectively;regional recurrences occurred in 11 patients（17.18%）.CONCLUSIONS： A criteria of OLP canceration was established,which solved the disagreement with OLP canceration by Krutchkoff et al;treatment of OLP canceration should be comprehensive.
出处
《中国口腔颌面外科杂志》
CAS
2011年第6期518-520,共3页
China Journal of Oral and Maxillofacial Surgery
关键词
口腔扁平苔藓
癌变
鳞状细胞癌
综合治疗
Oral lichen planus
Canceration
Squamous cell carcinoma
Comprehensive treatment
