连续硬膜外自控镇痛对剖宫产术后产妇恢复及血清泌乳素的影响

Effect of patient controlled epidural analgesia on recovery and serum prolactin of parturient after undergoing cesarean section

目的探讨连续硬膜外自控镇痛对剖宫产术后产妇恢复及血清泌乳素的影响。方法将86例行剖宫产术产妇按随机数字表法分为两组，观察组43例采用连续硬膜外自控镇痛，对照组43例采用哌替啶肌肉注射，比较两组的镇痛效果及血清泌乳素水平变化。结果观察组镇痛优良率[79．1％（34／43）]明显高于对照组[20．9％（9／43）]（P〈0．05）。观察组术后泌乳素水平[（542．17±46．75）μg/L]较术前[（351．13±20．92）μg/L]明显升高（P〈0．05），且明显高于对照组术后[（362．12±24．33）μg／L]（P〈0．05）。观察组的初乳时间[（15．21±3．26）h]明显早于对照组[（21．16±4．78）h]（P〈0．05）。结论连续硬膜外自控镇痛对剖宫产术后产妇进行镇痛，可以达到良好的镇痛效果，有利于产妇的恢复，促进血清泌乳素的分泌，值得临床推广应用。

Objective To discuss the effect of patient controlled epidural analgesia on recovery and serum prolaetin of parturient after undergoing cesarean section. Methods Eighty-six cases with cesarean section patients were classified into two groups by random digits table, which observation group with 43 cases were used patient controlled epidural analgesia, and control group with 43 cases were used intramuscular pethidine. The analgesic effect and serum prolactin between the two groups were compared. Results The good rate in observation group was 79.1% （34/43）, significantly higher than that in control group [ 20.9% （9/43） ] （P 〈 0.05 ）. Compared with pre-operation, the level of prolactin in observation group was significantly increased [ （ 542.17± 46.75 ） μ g/L vs. （351.13 ± 20.92 ） μ g/L ] （ P 〈 0.05 ）. Moreover, the level of prolactin in observation group after operation was significantly higher than that in control group [ （362.12± 24.33 ） μ g/L ] （P 〈 0.05 ）. The colostrum time in observation group was （ 15.21± 3.26 ） h which was shorter than that in control group [ （21.16 ± 4.78 ） h ] （P 〈 0.05 ）. Conclusion The analgesic effect of patient controlled epidural analgesia on parturient after undergoing cesarean section is good, which can help patients recovery and improve the level of serum prolactin, which can be applied in clinic.