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华法林对老年房颤患者抗凝疗效及安全性 被引量:2

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摘要 目的回顾性分析华法林在老年房颤患者中的抗凝疗效及安全性。方法选择36例年龄≥65岁房颤患者,在常规治疗的基础上,加服华法林随访观察2年,国际标准化比值(INR)保持在2.0~3.0。将服用华法林坚持2年者19例作为治疗组,另外未能坚持服用华法林者17例为对照组。比较两组间栓塞事件发生率、出血率。结果治疗组失访1例,观察期间无一例出现栓塞并发症,出血并发症3例(占16.7%),均为小量出血;对照组栓塞并发症3例(占17.6%),无出血并发症。对照组栓塞并发症与治疗组比较差异有统计学意义(P<0.05)。治疗组出血患者停用或减少华法林用量使INR保持在2.0~3.0,未再发生出血现象,能继续服药。结论老年房颤患者在合理监测INR情况下应用华法林预防栓塞并发症安全有效。
作者 卢革新
出处 《临床医学》 CAS 2011年第9期37-38,共2页 Clinical Medicine
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参考文献5

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