摘要
目的探讨妊娠期肝内胆汁淤积症(ICP)对胎儿的影响。方法选择孕足月ICP产妇40例为观察组(ICP组),正常孕足月产妇40例为对照组,分娩后测定脐静脉血清胆汁酸(TBA)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、肿瘤坏死因子-α(TNF-α)。结果 ICP组脐静脉血清胆汁酸(TBA)、ALT、AST、TNF-α均明显高于正常组,差异有统计学意义(P<0.05)。结论 ICP能造成胎儿肝功能异常,能导致胎儿有害细胞因子增加。
Objective To explore the effection of intrahepatic cholestasis of pregnancy（ICP）on the fetus.Methods Forty cases of ICP full-term pregnant women in the observation group（ICP group）,40 cases of normal full-term mothers as the control group,measured umbilical vein serum bile acid（TBA）,ALT,AST and TNF-α after delivery respectively.Results The umbilical vein serum bile acid（TBA）,ALT,AST and TNF-α of ICP group were significantly higher than those of the normal group（P0.05）.Conclusion ICP can cause fetal liver dysfunction and increase fetal harmful cytokines.
出处
《临床医学》
CAS
2011年第10期22-23,共2页
Clinical Medicine
关键词
妊娠
肝内胆汁淤积
胆汁酸
Pregnancy
Intrahepatic cholestasis
Bile acid
