摘要
目的:评价"葶苈大枣泻肺汤"治疗结核性胸膜炎的辅助疗效和安全性。方法:检索中国知网期刊全文数据库、中国生物医学文献数据库、万方数据库等数据库中所有有关"葶苈大枣泻肺汤"联合抗结核药治疗结核性胸膜炎的临床随机对照实验文献,采用Cochrane协作网提供的RevMan 4.2.10软件对数据进行系统分析。结果:最终纳入12篇文献进行分析;结果表明"葶苈大枣泻肺汤"能显著增加结核性胸膜炎的治愈率(P<0.000 01);减轻抗结核药的不良反应如肝肾损害、胃肠道反应等;未见"葶苈大枣泻肺汤"引发不良反应的报道。结论:现有资料表明"葶苈大枣泻肺汤"对结核性胸膜炎具有较好的辅助治疗作用,安全性高。
OBJECTIVE: To evaluate the effective and safety of Tingli Dazao Xiefei Soup as a subsidiary therapy for tuberculous pleurisy.METHODS: The clinical randomized control trials(RCTs) about Tingli Dazao Xiefei Soup combined antituberculosis drugs for treatment of tuberculous pleurisy were retrieved from CNKI periodical full-text database,China biomedicine bibliographic database,WanFang database and so on,and the data were analyzed by using the RevMan 4.2.10 software available on Cochrane Collaboration.RESULTS: A total of 12 RCTs were collected.The results indicated that Tingli Dazao Xiefei Soup can significantly increase the cure rate of tuberculous pleurisy(P0.000 01) and attenuate the adverse reaction of antituberculosis drugs such as liver damage,kidney damage and gastrointestinal tract reaction.There are as yet no reports about adverse reactions induced by Tingli Dazao Xiefei Soup.CONCLUSION: The data show that Tingli Dazao Xiefei Soup has good subsidiary effective and good safety for tuberculous pleurisy.
出处
《中国医院用药评价与分析》
2011年第11期963-966,共4页
Evaluation and Analysis of Drug-use in Hospitals of China