摘要
目的:分析铜陵市人民医院药品不良反应(ADR)的一般情况及影响因素,为临床安全、合理用药提供参考。方法:以2010年1月—2011年6月上报的285例药品不良反应为对象,按患者性别、年龄、药品种类、给药途径、不良反应临床表现进行统计分析。结果:由抗菌药物导致的ADR最多,共149例,占总例数的52.28%;以静脉滴注方式引起的ADR为249例,占总例数的87.37%。ADR临床表现以皮肤及其附件损害最常见,共116例,占总例数的40.70%。结论:不良反应监测对于临床合理使用抗菌药物、避免或减少ADR发生是很有必要的。
OBJECTIVE：To analyze the adverse drug reactions（ADRs） occurred in Tongling Municipal People＇s Hospital and the influencing factors so as to provide references for clinic safe and rational drug use.METHODS： A total of 285 ADR cases collected from Jan.2010 to June 2011 were statistically analyzed in respect of patients＇ age and sex,categories of drugs that induced ADR,route of administration,the organs or systems involved and the clinical manifestations of the ADRs.RESULTS： Most of ADR cases were induced by antibiotics,accounting for 52.28%（149 cases）.249 cases（87.37%） were induced vial intravenous drip infusion.The ADRs manifested predominantly as damage of skin and its appendants,accounting for 40.70%（116 cases）.CONCLUSION： ADR monitoring is important for clinical rational use of antibiotics and avoiding or reducing ADR frequency.
出处
《中国医院用药评价与分析》
2011年第11期1034-1036,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
不良反应
分析
合理用药
Adverse drug reactions
Analysis
Rational drug use
