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肝细胞生长因子检测在急性脑梗死中的临床意义

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摘要 目的探讨急性脑梗死(ACI)患者血清肝细胞生长因子(HGF)水平变化的临床意义。方法采用双抗体夹心酶联免疫吸附法定量检测30例脑梗死患者和30例正常对照组的血清HGF水平。结果与正常对照组相比,脑梗死组在病程1、7、14、21d血清HGF浓度均显著增高(P<0.05)。脑梗死组恢复期前各时间点之间差异无统计学意义(P>0.05);不同程度神经功能缺损脑梗死患者在急性期的神经功能缺损程度越重,血清HGF水平越高,差异具有统计学意义(P<0.05)。结论血清HGF水平可作为检测ACI患者病情严重程度的生化指标,对判定病情进展及预后具有一定意义。
作者 杜贵胜 王金亭 赵诚 王明阳
机构地区 山东省胶南市人民医院
出处 《中国实用医药》 2011年第30期40-41,共2页 China Practical Medicine
关键词 急性脑梗死 肝细胞生长因子 临床意义
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献6

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二级参考文献18

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共引文献33023

中国实用医药
2011年 第30期

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