改良皮肤点刺试验在慢性荨麻疹中的应用研究

Application of an improved skin prick test in chronic urticaria

目的改良皮肤点刺试验在筛查皮肤过敏原中的应用评价。方法随机人选475例慢性荨麻疹患者，年龄3—81岁，分别进行改良法（240例）和传统法（235例）皮肤点刺试验，比较两种点刺方法的过敏原阳性检出率。结果过敏原总阳性检出率改良法为65．4％，传统法为67．2％，两组差异无统计学意义（P〉0．05），最常见的过敏原均为户尘螨。结论改良皮肤点刺试验能够为临床诊断提供可靠依据，而且操作过程更加简便、安全。

Objective To evaluate the performance of an improved skin prick test in the screening for allergens. Methods A total of 475 patients with chronic urticaria who aged from 3 to 81 years were enrolled in this study, and classified into the control group （n = 235） and research group （n = 240）. Traditional and improved skin prick test were conducted in the control and research group respectively. The allergen detection rate was compared between the two test methods. Results The allergen detection rate was 65.4% and 67.2% respectively for the improved and traditional skin prick test, respectively （P 〉 0.05）. House dust mites were the most common sensitizing agent. Conclusion The improved skin prick test can offer reliable evidence for clinical diagnosis with a relatively convenient and safe procedure.