摘要
目的:探讨Barrett食管的临床、病理学特点,并通过免疫组织化学的表达结果,证实Barrett食管与食管腺癌之间的关系。方法:对胃镜及病理资料进行分类整理,重新阅片,确诊为Barrett食管的病例均进行免疫组化检查。结果:35例经胃镜及病理诊断为Barrett食管的患者,结合免疫组化检查,发现伴有上皮不典型增生的病例CerbB-2、P53、Ki-67均有不同程度的表达。结论:Barrett食管是一种癌前病变,由Barrett食管发展为食管腺癌的危险性在增加,因此,提高对Barrett食管的早期诊断,做到早发现、早治疗,降低食管腺癌的发生,提高生存率有重要的意义。
Objective To investigate the clinical Barrett's esophagus,pathological characteristics,and the expression by immunohistochemistry results confirmed that Barrett esophagus and esophageal adenocarcinoma relationship.Methods Endoscopy and pathology were sorted and re- read the piece,cases diagnosed as Barrett's esophagus underwent immunohistochemical examination.Results 35 cases diagnosed by endoscopy and pathological cases of Barrett's esophagus,immunohistochemical examination revealed epithelial hyperplasia associated with cases of CerbB- 2,P53,Ki-67 expression in varying degrees.Conclusion Barrett esophagus is a precancerous lesion,Barrett esophagus by the development of the risk of esophageal adenocarcinoma is increasing,therefore,improve the early diagnosis of Barrett's esophagus,so early detection and early treatment to reduce the incidence of esophageal adenocarcinoma and improve.
出处
《吉林医学》
CAS
2011年第33期7080-7081,共2页
Jilin Medical Journal