山东沿海地区女性痛风临床特点的研究

Clinical features of gout in female residents in coastal regions of Shandong province

对比分析172例女性痛风与1067例男性痛风的临床特征、合并症及血生化检测指标，探讨山东沿海地区女性痛风的临床特点。结果显示，女性痛风有其独特的临床特点：发病年龄较晚；较少饮酒和肥胖；较易合并糖尿病和冠心病；较少合并痛风石；急性期较少使用药物缓解；较易出现上肢关节和足部其他跖趾关节的受累。提示在临床诊疗过程中应多加注意，以便早期发现、及时有效治疗并尽可能避免高危因素。

The clinical features of 172 female and 1 067 male residents with gout in the coastal regions of Shandong province were analyzed. The results showed that as compared with male patients the onset of gout occurred at an older age in the female patients, and there were less obesity and tophi as well as less alcohol consumption and medication needed in the female patients. However, comorbidity with diabetes mellitus and coronary heart disease, as well as involvement of upper limb and other metatarsophalangeal joints were more prevalent in the female patients.