摘要
丝氨酸蛋白酶抑制剂在寄生线虫抵抗宿主蛋白酶对虫体损伤、调控炎症与免疫应答以及获得营养中发挥重要作用,部分抑制剂还参与虫体的发育及生殖。该文对寄生线虫中的丝氨酸蛋白酶抑制剂研究进展作一综述。
Inhibitors of serine protease produced by parasitic nematodes play important roles in the protection of parasite from host enzyme and immune response to the parasite, and in the feeding, development and reproduction of the parasites. In this review, we describe the research advances on the inhibitors of serine protease in parasitic nematodes.
出处
《国际医学寄生虫病杂志》
CAS
2011年第6期344-349,共6页
International JOurnal of Medical Parasitic Diseases
基金
国家自然科学基金(81171599)
关键词
寄生线虫
丝氨酸蛋白酶抑制剂
免疫应答
Parasitic nematodes
Inhibitors of serine protease
Immune response