摘要
目的 观察妊娠高血压综合征患者及正常孕妇血清中钠、钙、镁离子的浓度,以探讨其与妊娠高血压综合征发病的关系.方法 选取妊娠高血压综合征患者60例,连续两天空腹采集孕妇外周血测定血钠、钙、镁浓度,并与正常妊娠妇女血钠、钙、镁浓度进行比较.结果 妊娠高血压综合征组患者血清钠、钙、镁均明显低于对照组孕妇(t值分别为10.8099、10.6739和8.3625,均P=0.0001);随着妊娠高血压综合征病情的加重,其血清钠、钙、镁浓度均逐渐降低,轻度子痫前期组镁离子浓度显著低于妊娠期高血压组(t=2.8734,P=0.005),重度子痫前期组镁离子浓度显著低于妊娠期高血压组(t=4.7514,P=0.0001)和轻度子痫前期组(t=3.1373,P=0.0041),子痫组镁离子浓度显著低于妊娠期高血压组(t=6.8417,P=0.0001)和轻度子痫前期组(t=3.8558,P=0.0009),与病情有关.结论 测定孕妇血清钠、钙、镁浓度有助于判断妊娠高血压综合征的病情,并及早进行干预.
Objective To explore the clinical value of serum sodium, calcium, magnesium level in patients with pregnancy-induced hypertension syndrome. Methods The levels of serum sodium, calcium, magnesium in 60 patients with pregnancy-induced hypertension syndrome were determined in continuous two days with fasting plasma and compared with those of 60 normal pregnant women. Results In pregnancy-induced hypertension group, serum sodium, calcium, magnesium levels were significantly lower than those in control group (t was 10.8099, 10. 6739 and 8. 3625 respectively, all P = 0. 0001 ). With pregnancy-induced hypertension worsened, serum sodium, calcium, magnesium concentrations decreased gradually. The serum magnesium concentration was significantly lower in mild pre-eclampsia group than in gestational hypertension group (t = 2. 8734, P = 0. 005 ), and in severe pre-eclampsia group it was significantly lower than that in gestational hypertension group (t =4.7514, P =0.0001 ) and in mild pre-eclampsia group (t =3. 1373, P =0.0041 ). The serum magnesium concentration was significantly lower in eclampsia group than in gestational hypertension group (t = 6.8417, P = 0.0001 ) and mild pre-eclampsia group ( t = 3. 8558, P = O. 0009). Conclusion The serum levels of sodium, calcium, magnesium may predict the severity of pregnancy-induced hypertension syndrome.
出处
《中国妇幼健康研究》
2011年第6期819-821,共3页
Chinese Journal of Woman and Child Health Research
关键词
妊娠高血压综合征
血清钠
血清钙
血清镁
pregnancy-induced hypertension syndrome
serum sodium
serum calcium
serum magnesium