输卵管通液术与中药治疗输卵管阻塞性不孕

Hydrotubation combining traditional Chinese medicine in treatment of fallopian tube obstructive infertility

目的 观察输卵管不孕症患者行输卵管通液术时配合中药对不孕症患者的临床疗效.方法 收集江苏省响水县人民医院自2008年10月至2011年1月收治的输卵管阻塞性不孕患者142例,随机分为观察组72例和对照组70例,两组均行输卵管通液术治疗,但观察组加用活血去瘀中药,每日清晨灌肠,每次100mL,10天1疗程,共3~5个疗程,经期停用.比较两组治疗后临床疗效及输卵管畅通程度.结果 观察组一年妊娠率为40.3%,总有效率为95.8%.对照组一年妊娠率为28.6%,总有效率为84.3%.两组比较有统计学意义（χ2=7.9,P〈0.05）.观察组与对照组在治疗后与治疗前相比较,Ⅰ度、Ⅱ度、Ⅲ度及Ⅴ度在输卵管阻塞方面均有显著性差异,χ2值分别为96.5、75.6、112.7、87.8,均P〈0.01.治疗后观察组在Ⅰ度、Ⅲ度及Ⅴ度方面与对照组比较,有统计学意义,χ2值分别为10.4、7.8、6.5、12.9,均P〈0.05.结论 输卵管插管通液术结合中药治疗输卵管阻塞性不孕症安全、效果好,值得临床推广.

Objective To evaluate the clinical therapeutic effect of hygrotubation combining traditional Chinese medicine in treatment of fallopian tube obstructive infertility. Methods From October 2008 to January 2011 142 eases of fallopian tube obstructive infertility were treated in People＇s Hospital of Xiangshui. They were randomly divided into experimental group （72 cases） and control group （70 cases） and underwent hydrotubation. But traditional Chinese medicine was also used in experimental group. The clinical therapeutic effects and unobstructed state of fallopian tube were compared between two groups. Results The one year pregnancy rate of experimental group and control group was 40.3% and 28.6% respectively, and total effective rate of them was 95.8% and 84.3% respectively. The differences were statistically significant （X2 = 7.9, P 〈 0.05 ）. Compared with the obstructive state before treatment, the obstructive state of Ⅰ degree, Ⅱ degree, Ⅲ degree and Ⅴ degree after treatment was significantly different both in experimental group and control group （X2 was 96.5, 75.6, 112.7 and 87.8 respectively, all P 〈0.01 ）. There were significant differences in Ⅰ degree, Ⅱ degree, Ⅲ degree and Ⅴ degree between two groups after treatment （X2 was 10.4, 7.8, 6.5 and 12.9 respectively, all P 〈 0.05 ）. Conclusion Hydrotubation combining traditional Chinese medicine is safe and effective in treatment of fallopian tube obstructive infertility, and it is worthy of elinieal applying.