子宫颈癌100例临床病理特征分析

Analysis of clinicopathologic features with cervical cancer:a report of 100 cases

目的:探讨绝经与未绝经子宫颈癌患者的临床病理特征。方法:分析100例子宫颈癌的临床资料,按绝经与否分为绝经组32例,未绝经组68例,对比2组患者临床表现、瘤体大小、病理类型、肿瘤分期及肿瘤转移情况,并进行统计学分析。结果:未绝经组接触性出血症状明显多于绝经组(P<0.01);2组阴道不规则流血症状差异有统计学意义(P<0.05);未绝经组瘤体大于绝经组(P<0.05);而病理类型方面,未绝经组非鳞癌比例大于绝经组(P<0.05);肿瘤分期方面,未绝经组明显早于绝经组,Ⅰ期及Ⅱ期所占比例较大,Ⅳ期较少(P<0.05);未绝经组肿瘤转移情况明显多于绝经组(P<0.05)。结论:未绝经子宫颈癌患者接触性出血表现明显,瘤体相对较大,非鳞癌比例高,虽分期较早,但容易转移,预后较差。

Objective：To acquire better diagnosis and treatment by analyzing clinicopathologic features of non-menopausal and menopausal patients with cervical cancer.Methods：The clinical data of 100 cases with cervical cancer were analyzed retrospectively,and divided into non-menopausal group（32 cases） and menopausal group（68 cases） according to menopausal or not.Clinical presentation,tumor size,histological type,tumor stage and tumor metastasis of the two groups were studied and processed statistical analysis.Results：The contact bleeding symptoms in the non-menopausal group were more than that of the menopause group（P0.01）,2 groups of irregular vaginal bleeding symptoms was significantly（P0.05）.The size of tumor in the non-menopausal group was bigger than that of the menopausal group（P0.05）;and the proportion of non-squamous cell carcinoma was also more than the menopausal group（P0.05）.The cases of the non-menopausal group had early tumor stage,more ⅠandⅡperiod and less Ⅳ period amount compared with menopause group.However,the tumor metastasis cases in the non-menopausal group were more than menopause group（P0.05）.Conclusions：The non-menopausal patients with cervical cancer can lead easeily to contact bleeding,and accompany with large tumor volume and high proportion non-squamous cell carcinoma.The tumor is easy to transfer and has poor prognosis although its tumor stage is early in the non-menopausal patient.