三芳胺合成的研究进展

Recent Progress in the Synthesis of Triarylamine

三芳胺化合物的合成方法主要有3种:(1)非金属催化的胺化反应;(2)铜催化的Ullmann反应,包括使用过量铜粉为催化剂的传统的Ullmann反应、使用相转移催化剂的Ullmann反应以及使用配体的post-Ullmann反应;(3)钯催化的Buchwald-Hartwig反应.该类反应活性的关键是配体的选择,根据配体结构的不同可分为双膦螯合型配体、单膦配体和非膦配体.对该类化合物的这几种合成方法的研究进展进行了总结.

Three different synthetic methods have been developed for the triarylamine：（1） non-metal cata-lyzed amination reaction;（2） Ullmann reaction which can be divided to traditional Ullmann reaction using excess copper as catalyst,using phase-transition-catalyst as auxiliary and post-Ullmann reaction using ligand;（3） Buchwald-Hartwig reaction catalyzed by palladium complexes.The key issue for the activity of this reaction is the structure of ligand.There are three types ligand： chelate diphosphine ligand,mono-phosphine ligand and non-phosphine ligand.This review is focused on the recent progress of the synthetic methods of triarylamine.