复方苦参结肠溶胶囊联合SASP治疗溃疡性结肠炎20例

ANALYSIS OF COLONICCOATED COMPOUND LIGHTYELLOW SOPHORA ROOT CAPSULES COMBINED SULFASALAZINE IN TREATMENT OF 20 CASES ULCERATIVE COLITIS

目的:探讨复方苦参结肠溶胶囊联合柳氮磺胺吡啶(SASP)治疗溃疡性结肠炎(UC)的临床疗效。方法:40例轻、中度活动期UC患者随机分为两组(n=20),治疗组患者给予复方苦参结肠溶胶囊联合SASP治疗,对照组患者单纯应用SASP治疗。观察两组的治疗效果。结果:治疗组的总有效率为90%,明显高于对照组的70%(P<0.05);治疗组患者治疗后主要症状(腹痛、腹泻、粘液血便、里急后重)的改善情况明显优于对照组(P<0.05)。结论:复方苦参结肠溶胶囊联合SASP治疗UC效果显著,优于单用SASP。

Objective：To investigate the therapeutic effects of coloniccoated compound lightyellow sophora root capsules combined sulfasalazine （SASP） in treatment of ulcerative colitis （UC） patients.Methods：40 patients with mild or moderate UC （active phase） were randomly divided into 2 groups with 20 patients in each group. The patients in treatment group were given coloniccoated compound lightyellow sophora root capsules combined SASP; while the patients in control group were treated by SASP only. The therapeutic effects of 2 groups were observed after treatment.Results：The total effective rate of treatment group was 90%, which was obviously higher than that of control group （70%,P〈 0.05）. The main symptoms of UC （include abdominal pain, diarrhea, mucus bloody stool and tenesmus） were obviously improved for patients in treatment compared with control group （P〈 0.05）.Conclusions：Combination of coloniccoated compound lightyellow sophora root capsules and SASP can get obvious therapeutic effects in treatment of UC and is better than using SASP only.