奥扎格雷钠与丁咯地尔注射液治疗椎-基底动脉供血不足的疗效观察

The Efficacy of Ozagrel Combined with Buflomedil Injection in Treatment of Vertebral-Basilar Artery Insufficiency

目的探讨奥扎格雷钠与丁咯地尔注射液治疗椎-基底动脉供血不足的疗效及安全性。方法将确诊的100例患者随机分成治疗组(奥扎格雷钠与丁咯地尔+丹参)及对照组(丹参)两组,用药后观察比较两组疗效及治愈时间;两组治疗前后椎基底动脉系统TCD时间平均流速的变化情况。结果治疗组总有效率为92.0%,明显高于对照组(P<0.05)。治疗组平均治愈时间明显短于对照组(P<0.05)。治疗组左椎动脉TAV、右椎动脉TAV、基底动脉TAV治疗后较对照组改善明显。结论奥扎格雷钠与丁咯地尔注射液治疗椎-基底动脉供血不足疗效确切,值得临床推广。

Objective To investigate the efficacy and safety of ozagrel combined Buflomedil injection in treatment of vertebral-basilar artery insufficiency. Methods All of 100 patients were randomly divided into treatment group （with Ozagrel Buflomedil ＋ SM） and the control group（SM） groups, to observe the efficacy and healing time; two groups before and after treatment of vertebral average basilar artery TCD velocity changes. Results The total effective rate was 92.0%, significantly higher （P〈O.05）. Treatment group, the average healing time was significantly shorter than the control group （P〈O.05）. Treatment group in the left vertebral artery TAV, the right vertebral artery TAV, TAV basilar artery after treatment than the control group improved more significantly. Conclusion Ozagrel and BUFLOMEDIL injection in the treatment of vertebral - basilar artery insufficiency is effective, worthy of promotion.