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血管内皮生长因子在甲状腺癌的表达及意义 被引量：4

Vascular endothelial growth factor in thyroid carcinoma and its significance
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摘要 血管内皮生长因子特异性作用于血管内皮细胞，通过促进内皮细胞的增生，增加血管通透性，以诱导肿瘤血管及淋巴管生成，在肿瘤的发生发展中起到关键作用。研究表明，VEGF及其受体的表达与甲状腺癌的发生，淋巴结转移，预后密切相关，抑制VEGF及其受体的表达在甲状腺未分化癌及髓样癌的治疗中有一定的应用前景。 Vascular endothelial growth factor （VEGF）- specific effects on vascular endothelial cells, by promoting endothelial cell proliferation, increased vascular permeability, to induce tumor angiogenesis and lymphangiogenesis in tumor development has played key role. Studies have shown, VEGF and its receptor expression and the incidence of thyroid cancer, lymph node metastasis, prognosis, inhibition of VEGF and its receptor expression in anaplastic thyroid cancer and medullary cancer treatment in a certain application.
作者 韩肖骅 马保金
机构地区 上海市静安区中心医院（华山医院静安分院）普外科
出处 《国际外科学杂志》 2011年第11期748-751,共4页 International Journal of Surgery
关键词 血管内皮生长因子 甲状腺肿瘤 淋巴转移 治疗 Vascular endothelial growth factor Thyroid neoplasms Lymphatic metastasis Therapy
分类号 R736.1 [医药卫生—肿瘤]
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参考文献22

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二级参考文献12

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共引文献8

同被引文献69

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引证文献4

二级引证文献8

国际外科学杂志
2011年 第11期

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