摘要
目的探讨燮理阴阳汤治疗围绝经期综合征的临床疗效。方法选择我院门诊围绝经期综合征患者318例,随机分为治疗组212例,对照组106例。治疗组应用燮理阴阳汤1剂,po,bid;对照组应用更年安片4片,po,tid。两组疗程均为21 d。对治疗组和对照组患者治疗前后的临床症状进行评分,判断疗效。分别测定治疗组治疗前后患者血清中促卵泡生成素(FSH)和雌二醇(E_2)的浓度。结果总有效率治疗组为98.60%,对照组为91.50%,P<0.01。治疗组治疗前后血清中FSH浓度分别为(58.79±30.86)、(59.34±29.33)mIU·L^(-1),P>0.05;E_2质量浓度分别为(30.18±42.16)、(40.60±42.16)pg·L^(-1),P<0.05。结论燮理阴阳汤能有效提高血中E_2浓度,改善围绝经期综合征症状。
AIM To study clinical efficacy of Xieliyinyang decoction on perimenopause syndrome. METHODS A total of 318 patients with perimenopause syndrome were divided into 2 groups at random: the test group (212 patients, treated with a dose of Xieliyinyang decoction, po, bid for 21 d) and the control group ( 106 patients, treated with 4 geng- nian'an tablets,po ,bid for 21 d). Before and after treatment, patients in 2 groups were scored according to their clinical symptoms. Meanwhile, senan follicle-stimulating honnone(FSH) and estradiol (E2) of patients in the test group were ob- served respectively. RESULTS The clinical effective rate of the test group was 98.60%, and that of the control group was 91.50%, P 〈 0.01. Before and after treatment, serum FSH of patients in the test group was (58.79 + 30.86) mIU'L-t and (59.34 + 29.33) mIU'L-1 respectively, P 〉 0.05; serum E2 of patients in the test group was (30.18 + 42.16) pg'L-1 and (40.60+42.16) pg'L-1 respectively, P 〈0.05. CONCLUSION Xieliyinyang decoction could increase serum Eo level effectively and improve svndlome.
出处
《中国临床药学杂志》
CAS
2011年第6期357-359,共3页
Chinese Journal of Clinical Pharmacy
基金
上海市闵行区科委基金(编号2005-069)
关键词
围绝经期综合征
燮理阴阳汤
临床疗效
perimenopause syndrome
Xieliyinyang decoction
clinical efficacy