糖尿病足的临床特点及内科综合治疗的临床分析

Clinical analysis on clinical characteristic and effect of medicine synthesis therapy for diabetic foot

目的：分析糖尿病足（DF）患者的临床特点及探讨内科综合治疗方案的效果。方法：收集住院的糖尿病足病例共88例,并对其临床资料进行回顾性分析。结果：糖尿病足高发在年龄70岁以上（36.36%）,病程10~15年（38.64%）;起疱是糖尿病足的主要诱因;神经缺血性溃疡最多占45.45%;足溃疡好发于足趾（51.82%）;本组病例糖尿病足以Wagner4级患者为主（27.27%）;糖尿病足患者合并糖尿病周围神经病变（86.36%）、糖尿病肾病（65.90%）、高血压（63.64%）、周围血管病变（59.09%）等;治疗后伤口创面愈合16例,好转50例,截肢19例,死亡3例。DF分级级别越高,治疗效果越差。结论：DF多为高龄且DM病程长的患者,常伴有多种相关并发症,综合治疗糖尿病足效果肯定,治愈好转率与Wanger分级有明显的负相关性。

Objective To analyze the clinical characteristics of diabetic foot and investigate the effect of medicine synthesis therapy.Method Total 88 cases of diabetic foot in hospital were collected to retrospectively analyze the clinical data.Results Diabetic foot most frequently occurred in the elderly diabetic patients of more than 70 years old（36.36%） and diabetic duration of 10~15 years（38.64%）.The blister was main motivation of diabetic foot.There were 45.45% ulcers with neuropathy combined with peripheral artery disease.The location of ulcers was mainly toe,27.27% of the ulcers were at the Wagner stage 4.Most of these patients had diabetic complications,including neuropathy（86.36%）,nephropathy（65.90%）,hypertension（63.54%）,peripheral vascular disease（59.09%） and so on.The therapeutic results of diabetic foot ulcers included cicatrization（16 cases）,amelioration（50 cases）,amputation（19 cases） and decease（3 cases）.The higher Wagner stage,the more poor treatment effect.Conclusion The investigation shows that diabetic foot most frequently occurrs in the diabetic patients with advanced age,long diabetic duration and more diabetic complications.The effect of medicine synthesis therapy is positive.The effective rate of diabetic foot has a obvious negative correlation with Wagner classify method.