小麦纤维素对肛门良性疾病术后排粪情况的影响

Influence of fiberform on defecation condition after surgery for benign anorectal lesion

目的探讨小麦纤维素对肛门良性病变手术后排粪情况的影响。方法将2009年10月至2010年2月间南京中医药大学附属第三医院收治的121例肛门良性病变手术患者按随机数字表法分为试验组（61例）和对照组（60例）。试验组口服小麦纤维素颗粒2周，对照组不采用任何泻药：比较两组术后排粪症状评分及患者满意度。结果术后7d，试验组较对照组排粪通畅度积分下降率为62．1％．粪便性状积分下降率为74．3％，排粪间隔积分下降率为80．2％，排粪疼痛积分下降率为77．5％．差异均有统计学意义（均P〈0．05）；术后14d，试验组上述症状积分下降率分别为58.3％、88．5％、82．8％和83．1％，差异均有统计学意义（均P〈0．01）。术后试验组患者满意度明显高于对照组（P〈0．05）。治疗组无一例患者出现腹痛、腹泻及药物依赖性等不良事件发生。结论小麦纤维素可有效预防肛门良性疾病术后粪便干燥、排粪不畅、肛门疼痛等排粪障碍。

Objective To explore the influence of fiberform on the defecation condition after surgery for benign anorectal lesion. Methods A total of 121 cases undergoing surgery for benign anorectal lesion at the Third Affiliated Hospital of Nanjing University of Traditional Chinese Medicine from October 2009 to February 2010 were randomly divided into the treatment group （n=61） and the control group （n=60） according to random number table. Patients in the treatment group received fiberform granule for 2 weeks while patients in the control group did not receive any medication to promote defecation. Postoperative defecation symptom scores and patient satisfaction were compared between the two groups. Results On postoperative day 7, patients in the treatment group had a lower defecation smoothness score （62.1% decrease）, lower fecal character score （74.3% decrease）, lower defecation interval score （80.2% decrease）, lower defecation pain score （77.5% decrease）, the differences were statistically significant. On postoperative day 14, the degree of decrease of the abovementioned score were 58.3%, 88.5%, 82.8% and 83.1%, respectively. Postoperative patient satisfaction rate in the treatment group was significantly higher than that in the control group （P〈 0.05）. No patient in the treatment group experienced any adverse events such as abdominal pain, diarrhea, and drug dependence. Conclusion Fiberform can effectively prevent defecation disorders such as dry stool, unsmooth defecation, and anoreetal pain.