新疆汉族、维吾尔族正常男性人群定量CT骨密度的差异性

Differences of Bone Mineral Density in Healthy Han and Uygur Males in Xinjiang Measured by Quantitative CT

目的测量新疆汉族、维吾尔族正常男性人群定量CT(QCT)骨密度(BMD)值,研究新疆地区正常男性人群骨密度现状,比较两种民族男性骨密度随年龄变化的规律及差异。资料与方法对20～82岁以上的704名符合健康标准的乌鲁木齐及周边地区汉族、维吾尔族男性体检者进行腰椎骨密度QCT测量,按不同民族每5岁分为1个年龄组,比较两组各年龄段骨密度及骨质疏松症患病率。结果汉族、维吾尔族男性腰椎出现骨峰值的年龄段相同,维吾尔族男性骨峰值较汉族男性高(P<0.05)。随年龄增大,两民族男性骨密度均逐渐下降。65岁以后,汉族、维吾尔族男性骨量有加速下降的趋势,骨质疏松症患病率增加,65岁组及≥70岁组汉族男性骨质疏松症患病率分别为15.91%、27.59%,维吾尔族男性骨质疏松症患病率分别为21.43%、36.84%,≥70岁组两组间比较,差异有统计学意义(P<0.05)。结论汉族、维吾尔族男性腰椎骨密度变化规律相似,65岁以上男性是骨质疏松症的高发人群,维吾尔族老年男性更易罹患骨质疏松症。

Purpose To investigate the status of bone mineral density （BMD） and the change with age by measuring BMD in healthy Han and Uygur males in Xinjiang with QCY. Materials and Methods 704 healthy Han and Uygur males aged 20 - 82 years in Xinjiang underwent quantitative CT （QCT） of lumbar vertebrae for bone mineral density （BMD） using multi-slice spiral CT （GE , America） and QCT-3000 System. The mean BMD value, standard deviation （SD） and the prevalence of osteoporosis were analyzed in different nationalities. The subjects were grouped according to age （per 5 years）. Results Peak BMD in lumbar spine was in same age groups in both Han and Uygur males, but the peak BMD in Uygur nationality was higher than that in Han （P 〈 0.05）. The BMD showed rapid decrease after 65 years of age. The prevalence of osteoporosis was increased in groups of 65 -70 years and≥70years, 15.91% and 27.59% respectively in Han males; 21.43% and 36.84% respectively in Uygur males. There was significant difference between Han and Uygur males when they were ≥ 70years （P 〈 0.05）. Conclusion This study shows the trends of BMD in Han and Uygar males are similar, and males above 65 years old tend to have higher risk of developing osteoporosis, especially in Uygar.