鬼箭锦鸡儿化学成分的研究

Chemical constituents of Caragana jubata(Pall.) Poir

目的研究鬼箭锦鸡儿的化学成分。方法采用溶剂浸取法提取,硅胶、Sephadex LH-20、半制备液相等色谱技术分离纯化,根据理化性质和光谱分析鉴定化合物的结构。结果从鬼箭锦鸡儿95%乙醇提取液的三氯甲烷萃取部位中分离得到6个化合物,分别鉴定为高丽槐素(Ⅰ)、芒柄花素(Ⅱ)、4-甲氧基苯甲酸(Ⅲ)、野靛黄素(Ⅳ)、2-甲氧基-4-乙氧基苯甲酸(Ⅴ)、7,3'-二羟基-5'-甲氧基异黄酮(Ⅵ)。结论化合物Ⅲ～Ⅵ为首次从鬼箭锦鸡儿中分离得到。

AIM To study the chemical constituents of Caragana jubata（Pall.） Poir..METHODS The compounds were extracted by solvent methods.Silica gel,Sephadex LH-20 column chromatographies and Semipreparative RP-HPLC were employed for the isolation and purification of chemical constituents.The structures were identified by physicochemical properties and spectroscopic evidence.RESULTS Six compounds were obtained from chloroform extract fraction of 95% ethanol extraction of Caragana jubata（Pall.） Poir..Their structures were identified as maackiain（Ⅰ）,formononetin（Ⅱ）,4-methoxy benzoic acid（Ⅲ）,pseudobaptigenin（Ⅳ）,2-methoxy-4-ethoxy benzoic acid（Ⅴ）,7,3′-dihydroxy-5′-methoxy isoflavone（Ⅵ）.CONCLUSION Compounds Ⅲ-Ⅵ are isolated from Caragana jubata（Pall.）Poir.for the first time.