河南省吸毒人群HIV/HCV感染状况分析

Prevalence and associated risk factors of HIV,HCV infection in drug users in Henan province

目的了解河南省吸毒人群人类免疫缺陷病毒(HIV)、丙型肝炎病毒(HCV)感染状况及其相关危险因素,为针对其制订艾滋病防治措施提供科学依据。方法于2009年1月-2010年6月对河南省美沙酮维持治疗门诊收治的836名吸毒者进行行为学和血清学调查,分析其HIV、HCV感染的危险因素。结果 836名吸毒者HIV抗体阳性者12例,阳性率为1.44%,HCV抗体阳性者32例,阳性率为3.83%;HIV/HCV合并感染率为0.8%(7/836);近半年吸毒方式为单纯注射的人群合并感染率为12.1%(7/58);曾共用针具人群的合并感染率为9.5%(2/21);20.5%(171/836)的吸毒者曾注射过毒品;66.7%(565/836)的吸毒者曾戒毒,但均未成功;在进入美沙酮门诊时59.7%(499/836)的研究对象尿检阳性,提示近期曾使用毒品。结论吸毒人群是HIV、HCV感染的易感人群,同时其存在多种导致HIV传播的危险因素;应加强美沙酮维持治疗,降低吸毒人群高危行为,遏制艾滋病在该人群中的传播。

Objective To examine the prevalence and associated risk factors of human immunodeficiency virus（HIV） and hepatitis C virus（HCV） infection in drug users with methadone maintenance treatment（MMT）and to provide scientific evidence for AIDS prevention strategy among intravenus drug users（IDUs） in Henna province.Methods Information on behavior and serological test were collected among 836 IDUs with MMT in Henan province to explore the risk factors of HIV,HCV infection.Results The prevalence of HIV infection among the IDUs was 1.44%（12/836）and the HCV infection rate was 3.83%（32/836）,with a HIV/HCV co-infection rate of 0.8%（7/836）.Risk factors of HIV,HCV infection included nationality,drug use,means of drug use,and needle sharing.Conclusion IDUs are susceptible population of HIV,HCV infection and there are various risk factors lead to HIV transmission.Methadone maintenance treatment is an effective measure to control high risk behaviors in IDUs and AIDs transmission in the population.