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基于磁力场与速度场协同的高效微通道磁泳分离 被引量：4

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摘要 磁泳是实现生化分离的重要手段之一.根据微通道内磁珠运动基本方程导出了影响磁泳分离效率的新因素,即磁场力矢量与流体速度矢量的夹角,提出改善磁力场与流场的协同性是提高磁泳分离效率的重要途径之一,并基于此设计了T型结构微通道磁泳分离芯片.通过建立磁珠运动的二维动力学模型,并运用有限元和龙格库塔法,对微通道内的磁泳分离效率进行了数值模拟研究.结果发现:相同条件下T型微通道分离效率较普通平直微通道明显提高;在高流速下直通道对小粒径磁珠的磁泳分离失效时,T型微通道仍能实现高效分离.进一步分析表明,T型微通道内分离效率提高的本质在于磁力场与流场的协同作用使得磁珠产生更大的偏转速度,从而增加了分离效率.研究结果对磁泳芯片优化设计具有理论指导意义.
作者 吴信宇 吴慧英 胡定华
机构地区 上海交通大学机械与动力工程学院
出处 《中国科学：技术科学》 EI CSCD 北大核心 2011年第12期1620-1627,共8页 Scientia Sinica(Technologica)
基金 国家杰出青年科学基金(批准号:50925624) 国家重点基础研究发展计划(批准号:2012GB720404) 上海市优秀学术带头人计划(批准号:11XD1403100)资助
关键词 磁泳分离 T型微通道 分离效率 场协同
分类号 O441.2 [理学—电磁学]
  • 相关文献

参考文献21

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共引文献6

同被引文献22

  • 1李强,宣益民,王健.磁流体粘度的实验研究[J].工程热物理学报,2005,26(5):859-861. 被引量：7
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引证文献4

二级引证文献3

中国科学：技术科学
2011年 第12期

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