TCT在宫颈疾病筛查中的应用

TCT in cervical disease screening applications

目的探讨宫颈液基薄片细胞学检测(TCT)在宫颈疾病筛查中的应用价值,了解其对宫颈癌前病变和宫颈癌诊断的可行性。方法回顾性分析320例妇科患者的一般资料,按照自愿、对照的原则分为观察组和对照组,各为160例。观察组患者采用TCT检查,对照组患者采用巴氏涂片进行检查。观察和比较两组宫颈病变活检结果及标本满意率。结果观察组160例患者中组织学诊断阳性结果 121例,诊断符合率为75.6%;对照组160例患者中组织学诊断阳性结果 92例,诊断符合率为57.5%,两组比较观察组诊断符合率明显高于对照组,差异具有统计学意义(P<0.01);观察组标本满意145例,满意率为90.6%,对照组标本满意123例,满意率为76.9%,两组比较观察组标本满意率明显高于对照组,差异具有统计学意义(χ~2=11.11,P<0.01)。结论与巴氏涂片方法相比,TCT能显著地提高宫颈病变的检出率,提高细胞学检查的质量,为临床及时发现宫颈早期病变,给予有效的治疗提供了临床依据,也是防治宫颈癌发生的有力措施,值得临床进一步推广应用。

Objective To explore the Thinprep cytologic test(TCT) in cervical disease screening of applications,to understand their diagnosis of cervical lesions and cervical cancer viability.Methods Retrospective analysis of 320 cases of gynecological patients with general information.Accordance with the voluntary control of the principle of divided into two groups Observation group and control group,each with 160 cases.Observation group were treated with TCT examination,the control group patients with Pap smears to check.Observed and compared the results of two groups of cervical lesions and biopsy specimens of satisfaction.Results The Observation group 160 patients in the histological diagnosis of 121 cases of positive results, diagnostic rate of 75.6%.160 patients in the control group,histological diagnosis of 92 cases of positive results,diagnostic accuracy rate of 57.5%.the observation group was significantly higher diagnostic accuracy,the difference was statistically significant(P <0.01).Specimens satisfied the observation group,145 cases satisfaction rate of 90.6%in the control group specimens satisfied with 123 cases,76.9%satisfaction rate,the two groups,the observation group was significantly higher satisfaction rate specimens,the difference was statistically significant(x^2=11.11,P <0.01 ).Conclusion Compared with the Pap smear method,TCT could very significantly improve the detection rate of cervical lesions and improve the quality of cytology for the timely detection of early cervical lesions clinically,give effective treatment to provide a clinical basis,but also the Drevention of cervical cancer effective measures to happen.was worthv of further application.