草决明药理作用的研究

Study on pharmacology of cao Jueming

目的:研究草决明提取物对正常小鼠的血清总胆固醇影响,对高血脂症大白鼠的血脂影响,对大白鼠的棉球肉芽肿影响。方法:建立小白鼠和大白鼠高脂血症模型,给予草决明提取物治疗,研究草决明对小白鼠血清总胆固醇、对大白鼠血脂以及对大白鼠棉球肉芽肿的影响。结果:通过上述动物实验,证明草决明具有显著的保肝、利胆、降血压、降血脂作用,并有一定的抗动脉粥样硬化作用,是一种安全药物。结论:草决明安全、有效,可以应用于临床。

Objective：To research the cao Jueming on normal small rats serum total cholesterol, antioxidationin experimental hyperlipidemia rats, to send the mouse ear swelling function and the tip of toe swelling degree to the car -rageenin of the function. Methods： Establish the hyperlipidemia in model, gave the cao Jueming, research cao Jueming on the various indexes of lipid and antioxidation including the total cholesterol （TC）, the blood lipidmetabolism and the tip of toe swelling degree to the carrageenin of the function. Results： The results showed that cao Jueming had the significant to protect the liver, bravery, reduce the blood -lipid, reduced blood pressure effects,and had some resist the atherosclerosis, it was a safe medicine. Conclusion： Jueming 草决明is safety, effective,and can be used in clinic.