rPA溶栓治疗急性肺血栓栓塞的观察与护理

rPA thrombolytic treatment of acute pulmonary thromboembolism observation and care

目的观察应用r-PA溶栓治疗急性肺动脉血栓栓塞的疗效,总结护理经验。方法对52例经CT证实为急性肺动脉血栓栓塞的患者给予r-PA18 mg加NS10 ml静脉注射进行溶栓治疗,注射时间大于2 min,观察溶栓前及溶栓4h后患者的临床症状、血氧饱和度、螺旋CT肺动脉成像及动脉血氧分压的变化。结果应用r-PA对52例急性肺动脉血栓栓塞患者溶栓后8,4.61%的患者临床症状改善,氧饱和度上升,动脉氧分压升高,肺动脉压下降,与溶栓前比较差异显著(P<0.01)。结论 r-PA静脉溶栓治疗急性肺动脉血栓栓塞有较好的临床疗效与安全性,严密观察病情及时采取相关护理措施是促使病情恢复的保障。

Objective： To observe the rPA thrombolytic therapy in the treatment of acute pulmonary thromboembolism, and to summary nursing experience. Methods ： Firty - two cases confirmed by CT of acute pulmonary thromboembolism were treated with rPA18mg plus NS10ml intravenous thrombolytie therapy, with the injection time of more than 2min, and clinical symptoms, blood oxygen saturation, spiral CT imaging and pulmonary arterial oxygen partial pressure changes were ob- served 4h after thrombolysis and thrombolysis in the patients. Results： rPA in 52 patients with acute pulmonary thromboembolism in patients after thrombolysis, 84.61% of patients had clinical improvement, oxygen saturation and arterial oxygen pressure increased and pulmonary artery pressure decreased, with significant difference before thrombolysis （ P 〈 0.01 ）. Conclusion ： rPA thrombolytic therapy in acute pulmonary thromboembolism has better clinical efficacy and safety, close observation and related care should be done to take timely measures to promote disease recovery protection.